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Description

Cifran® Eye and Ear Drops are manufactured by Sun Pharma and comprise Ciprofloxacin as an active ingredient, which is a synthetic broad-spectrum antibiotic from the drug class Fluoroquinolones (2nd generation).

Indications:

- bacterial eye infections (conjunctivitis, corneal ulcers, superficial infections of the eye and adnexa);

- bacterial ear infections (otitis externa, acute otitis media, chronic suppurative otitis media);

- prophylaxis in otic surgeries such as mastoid surgery.

MOA (mechanism of action):

Ciprofloxacin is a synthetic antimicrobial agent that exhibits its bactericidal action through inhibiting the bacterial DNA gyrase enzyme, required for bacterial DNA replication, transcription, repair and recombination. Ciprofloxacin is effective against Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus epidermidis and Streptococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Campylobacter jejuni, Shigella flexneri and Shigella sonnei.

Dosage

For corneal ulcers: instill 2 drops into the treated eye every 15 minutes for the first 6 hours and then 2 drops into the treated eye every 30 minutes for the remainder of day 1.

Day 2: instill 2 drops in the treated eye hourly.

Day 3 - Day 14: instill 2 drops in the treated eye every 4 hours. Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

For conjunctivitis: instill 1 or 2 drops instilled into the conjunctival sac(s) every 2 hours, while awake, for 2 days and 1 or 2 drops every 4 hours, while awake, for the next 5 days.

For superficial eye infection: instill 1 or 2 drops in the treated eye(s) 4 times a day. In severe infections, the dosage for the first 2 days may be 1 or 2 drops every 2 hours while awake.

The maximum duration of therapy of 21 days is recommended.

For ear infections: instill 2-3 drops every 2-3 hours initially, reducing the frequency of the instillation with control of infection.

Precautions:

Cifran® Eye and Ear Drops are not for use in children under 1 year.

Ciprofloxacin solution is not for injection.

Ciprofloxacin solution is associated with allergic reactions, even following a single dose. Discontinue using drops immediately and contact your physician at the first sign of a rash or allergic reaction.

Prolonged use of Cifran® Eye and Ear Drops may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue using these drops and institute alternative therapy.

Avoid contaminating the applicator tip with eye, fingers or another source.

Cifran® Eye and Ear Drops may cause your vision to blur temporarily after you have applied them into your eye. Do not drive or operate machinery until this has worn off.

Patients should not wear contact lenses while using Ciprofloxacin solution for eye infection.

Wash your hands before using the eye and ear drops.

Missing a dose

If you miss a dose you should instill it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

Overdose

If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately. A topical overdose of Cifran® Eye and Ear Drops may be flushed from the eye(s) with lukewarm tap water.

Storage

Store at cool room temperature, away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use. Use within one month after opening a container. Keep out of the reach of children.

Side effects

The most common side effects associated with Cifran® Eye and Ear Drops are:

  • If applied to eyes:
  • corneal deposits
  • discomfort
  • hyperaemia
  • If applied to ears:
  • ear pain

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Cifran® Eye and Ear Drops are not for use in infants under 1 year of age.

Do not use Cifran® Eye and Ear Drops if you are allergic to Ciprofloxacin or to other Fluoroquinolones.

Do not use Cifran® Eye and Ear Drops if you are allergic to any ingredient comprised in Cifran® Eye and Ear Drops.

Do not use Cifran® Eye and Ear Drops if you have a history of severe allergic reactions associated with using antibiotics.

Do not use Cifran® Eye and Ear Drops in combination with products or medications containing caffeine, anticoagulants (warfarin), cyclosporines.

Patients should not wear contact lenses while using Ciprofloxacin solution for eye infection.

Consult your doctor before using Cifran® Eye and Ear Drops if you are pregnant, plan to have a baby or are breastfeeding.

Q: What are Cifran® Eye and Ear Drops used for?

A: Cifran® Eye and Ear Drops is used as first-line therapy of bacterial infections of the eyes or ears in adults and children. Suitable for conjunctivitis, corneal ulcers, superficial ocular infection, otitis externa, otitis media etc. Not for injection.

Q: Are Cifran® Eye and Ear Drops safe?

A: Cifran® Eye and Ear Drops are safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q: Can I use Cifran® Eye and Ear Drops for a fungal infection?

A: Cifran® Eye and Ear Drops will not work for viral infections (colds, flu) and for infections caused by mycoses (fungi).

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).

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